{"id":2882,"date":"2017-10-30T18:47:43","date_gmt":"2017-10-30T18:47:43","guid":{"rendered":"https:\/\/screening.mhanational.org\/article\/monoamine-oxidase-inhibitors-maois\/"},"modified":"2023-07-06T11:32:39","modified_gmt":"2023-07-06T15:32:39","slug":"monoamine-oxidase-inhibitors-maois","status":"publish","type":"article","link":"https:\/\/screening.mhanational.org\/es\/content\/monoamine-oxidase-inhibitors-maois\/","title":{"rendered":"Inhibidores de la monoaminooxidasa (IMAO)"},"content":{"rendered":"<p>Monoamine oxidase inhibitors (MAOIs) are one of the oldest types of <a href=\"https:\/\/screening.mhanational.org\/es\/content\/what-meds-treat-depression\/\">antidepresivos <\/a>still in use. Now that there are more alternatives available, MAOIs are not used as often as they used to be.<\/p>\n<p>MAOIs can interact with a lot of other medications, which makes them hard to use alongside other medications. (You generally need to be off an MAOI for about 2 weeks before starting another antidepressant.) They can also trigger allergic reactions to certain foods, so being on them often involves dietary restrictions.<\/p>\n<p>Still, MAOIs can be helpful if other types of antidepressants haven\u2019t worked. They are sometimes used to <a href=\"https:\/\/screening.mhanational.org\/es\/content\/what-meds-treat-bipolar\/\">treat bipolar disorder<\/a>, or to treat neurological conditions such as Parkinson\u2019s disease.<\/p>\n<p>Tambi\u00e9n pueden ser \u00fatiles para <strong>depresi\u00f3n at\u00edpica<\/strong>, or \u201cdepression with atypical features.\u201d In addition to the regular symptoms of depression, these \u201catypical features\u201d are:<\/p>\n<ul>\n<li>Weight gain or increased appetite<\/li>\n<li>Sleeping too much<\/li>\n<li>A sense of heaviness in the arms and legs (\u201cleaden paralysis\u201d)<\/li>\n<li>Being extremely sensitive to social rejection<\/li>\n<\/ul>\n<p>Other possible symptoms of atypical depression include:<\/p>\n<ul>\n<li>Intensely craving attention<\/li>\n<li>Panic attacks and anxiety<\/li>\n<li>Increased sexual desire<\/li>\n<\/ul>\n<h2>Examples of MAOIs<\/h2>\n<table class=\"table table-bordered table-striped\">\n<thead>\n<tr>\n<th>Nombre gen\u00e9rico<\/th>\n<th>Marca(s) comercial(es)<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>isocarboxazida<\/td>\n<td>Marplan<\/td>\n<\/tr>\n<tr>\n<td>fenelzina<\/td>\n<td>Nardil<\/td>\n<\/tr>\n<tr>\n<td>Selegilina<\/td>\n<td>EMSAM<\/td>\n<\/tr>\n<tr>\n<td>Tranilcipromina<\/td>\n<td>Parnate<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>EMSAM (or selegiline) is unique among MAOIs\u2014and other antidepressants. Instead of a pill, it comes as a skin patch. There is some evidence that it may be more effective and have fewer side effects than other MAOIs.<\/p>\n<h2>How do MAOIs work?<\/h2>\n<p>Like other mental health medications, MAOIs work by restoring the balance of the chemicals in your brain. These chemicals are called <strong>neurotransmisores<\/strong>. The main neurotransmitters affected by antidepressants are:<\/p>\n<ul>\n<li><strong>Serotonina<\/strong>, which affects your mood, energy level, appetite, and sleep.<\/li>\n<li><strong>Dopamina<\/strong>, which affects motivation and pleasure. Sometimes called the \u201cfeel good chemical.\u201d<\/li>\n<li><strong>Norepinefrina<\/strong>, which affects your energy level, focus, and attention. Related to adrenaline and has similar effects.<\/li>\n<\/ul>\n<p>Most antidepressants mainly boost serotonin levels. MAOIs boost all three. In fact, MAOIs helped scientists discover how these chemicals are involved in depression in the first place.<\/p>\n<h2>Side effects of MAOIs<\/h2>\n<p>Common:<\/p>\n<ul>\n<li>Dizziness and fainting<\/li>\n<li>Drowsiness, or trouble sleeping<\/li>\n<li>Nausea<\/li>\n<\/ul>\n<p>Less Common:<\/p>\n<ul>\n<li>Weight gain<\/li>\n<li>Muscle cramps or involuntary muscle jerks<\/li>\n<li>Reduced sexual desire or difficulty reaching orgasm<\/li>\n<li>Increased blood pressure<\/li>\n<li>Prickling or tingling sensation in the skin (paresthesia)<\/li>\n<li><strong>S\u00edndrome serotonin\u00e9rgico<\/strong>, a rare but serious condition involving twitching, sweating, shivering, diarrhea, or seizures. Talk to your doctor right away if you experience signs of serotonin syndrome.<\/li>\n<\/ul>\n<p><a class=\"button blue round caret collapsed\" href=\"#references\" data-toggle=\"collapse\" aria-expanded=\"false\" aria-controls=\"references\" data-toggle-text=\"Hide References\">Mostrar referencias<\/a><\/p>\n<div id=\"references\" class=\"references collapse\">\n<ul>\n<li>Asnis &amp; Henderson. (2014). EMSAM (deprenyl patch): how a promising antidepressant was underutilized. <em>Neuropsychiatric Disease and Treatment 10<\/em>, pp. 1911-1923. Retrieved from <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4200016\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4200016\/<\/a><\/li>\n<li>Fiedorowicz y Swartz. (2004). El papel de los inhibidores de la monoaminooxidasa en la pr\u00e1ctica psiqui\u00e1trica actual. <em>Revista de Pr\u00e1ctica Psiqui\u00e1trica 10<\/em>(4), pp. 239-248. Obtenido de <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2075358\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2075358\/<\/a><\/li>\n<\/ul>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Monoamine oxidase inhibitors (MAOIs) are one of the oldest types of antidepressants still in use. Now that there are more alternatives available, MAOIs are not used as often as they used to be. MAOIs can interact with a lot of other medications, which makes them hard to use alongside other medications. (You generally need to &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/screening.mhanational.org\/es\/content\/monoamine-oxidase-inhibitors-maois\/\" class=\"more-link\">Seguir leyendo<span class=\"screen-reader-text\"> &#8220;Monoamine oxidase inhibitors (MAOIs)&#8221;<\/span><\/a><\/p>","protected":false},"author":14,"featured_media":0,"template":"","age_group":[23,100,19],"condition":[83,84,86],"class_list":["post-2882","article","type-article","status-publish","hentry","age_group-11-17","age_group-over-18","age_group-under-11","condition-anxiety","condition-bipolar","condition-depression"],"acf":[],"yoast_head":"<title>Monoamine oxidase inhibitors (MAOIs)<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/screening.mhanational.org\/es\/content\/monoamine-oxidase-inhibitors-maois\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Monoamine oxidase inhibitors (MAOIs)\" \/>\n<meta property=\"og:description\" content=\"Monoamine oxidase inhibitors (MAOIs) are one of the oldest types of antidepressants still in use. 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