Antipsychotics are a type of medication, used to treat a variety of mental health conditions. Their main uses are for mental illnesses that include psychotic symptoms, such as schizophrenia or bipolar disorder. But they’re also used for other conditions, such as depression, anxiety, and difficulty sleeping.
Antipsychotics work by impacting neurotransmitters—chemical messengers used to communicate between brain cells. Dopamine is the main neurotransmitter affected by these medications. If parts of the dopamine system become overactive, they seem to play a part in producing hallucinations, delusions, and thought disorders. Antipsychotics block some of the receptors that react to dopamine.
Examples of antipsychotics include:
|Generic name||Brand name(s)|
|Fluphenazine||Prolixin, Modecate, Moditen|
|Perphenazine||Trilafon, Etrafon, Triavil, Triptafen|
|Prochlorperazine||Compazine, Compro, Darbazine, Neo Darbazine|
These medications are sometimes called “typical antipsychotics,” or “first-generation antipsychotics.” There is also another class of medications called “atypical antipsychotics,” or “second-generation antipsychotics.”
Atypical antipsychotics are newer. They tend to be used more commonly nowadays, because they are less likely to cause side effects. First-generation antipsychotics like the ones listed here are generally used after someone has tried other medications with no success.
Like all medications, antipsychotics can cause side effects. Finding the right treatment for a mental health condition is a balancing act—you and your doctor work together to weigh the potential benefits of a medication against the potential side-effects. Medications affect each person differently, so this usually involves some trial and error.
Common side-effects of antipsychotics include:
- Stiffness and shakiness
- Feeling sluggish and slow in your thinking
- Uncomfortable restlessness
- Increased blood pressure
- Decreased sex drive
- Breast swelling or tenderness
- Weight gain
- Dry mouth
- Blurred vision
Less common side effects include:
- Involuntary body movements or facial tics (tardive dyskinesia and other movement disorders)
- Decreased white blood cell production/reduced immune function
- Heart attack
If you experience any of these symptoms while taking an antipsychotic medication, speak with your doctor. Your doctor will work with you to determine the best way forward.
- Lacey, Michael. “Antipsychotics.” Antipsychotic Medication, Royal College of Psychiatrists, Jan. 2014, www.rcpsych.ac.uk/healthadvice/treatmentswellbeing/antipsychoticmedication.aspx